Sunday, April 25, 2010

H. Pylori increased risk for polyps

"Blacks with Helicobacter pylori infection were at an increased risk for developing colorectal polyps, according to the results of a retrospective study presented at the American Association for Cancer Research 101st Annual Meeting in Washington, D.C.

“This infection is more common in minorities and African Americans and there is a higher incidence of colon cancer and mortality from colon cancer in African Americans compared with Caucasians,” said Duane T. Smoot, MD, chief of the gastrointestinal division at Howard University, Washington, D.C. “Currently, we think of H. pylori as an infection in the stomach that causes diseases in the stomach, but what we may not be aware of is how much it affects the colon.”

Smoot and colleagues examined 1,262 black patients who were enrolled the same day as bidirectional gastrointestinal endoscopy. H. pylori status was assessed using immunohistochemistry on gastric specimens; polyps were confirmed by histological examination from complete colonoscopy.

Polyps were 50% more prevalent among black patients with H. pylori compared with uninfected patients (43% vs. 34%; 95% CI, 1.2-1.9). In addition, data indicated a trend toward larger polyp size — greater than 1 cm — in patients infected with H. pylori (P=.07).

Certain participants were identified at baseline as having above average risk for colorectal polyps (n=21); polyps were detected in 62% of these patients. – by Leah Lawrence"

For more information on H. Pylori

1 comment:

mike said...

interesting relation between polyps and h pylori.

while this article is off topic, i think you may find it interesting.